The match at Loftus Versfeld will kick off at 19h00 and will be broadcast live on SuperSport.
The team from the Northern Cape have named three co-captains for the season in Whitehead, who will take the lead when he plays, as well as Zandre Jordaan and Monde Hadebe.
Tafel Lager Griquas coach Scott Mathie – a former Vodacom Blue Bulls scrumhalf in his playing days – has named a bunch of stalwarts for the trip to Pretoria, with the inclusion of James Verity-Amm on the left wing sure to get some attention in Australia.
The 26-year-old outside back is a former Western Province age-group representative, but he relocated to Australia a few years ago and has played for the Western Force and the Brumbies.
Mathie has named 11 players on the bench, but three names will have to be omitted on game day as teams are only allowed to play with squads of 23.
Former Springbok wing Bjorn Basson and Alandre van Rooyen, who moved to Kimberley from Port Elizabeth recently following the liquidation of the Southern Kings, are amongst the replacements.
The last time the men from Kimberley travelled to Pretoria was in the 2019 Currie Cup, when they upset the hosts at Loftus Versfeld by 37-15, and Mathie will no doubt be very happy if Tafel Lager Griquas can repeat that feat on Saturday.
Tafel Lager Griquas: 15 Anthony Volmink, 14 Daniel Kasende, 13 Harlon Klaasen, 12 Andre Swarts, 11 James Verity-Amm, 10 George Whitehead (captain), 9 Zak Burger, 8 Niell Jordaan, 7 Stefan Willemse, 6 Carl Els, 5 Victor Sekekete, 4 Ian Groenewald, 3 John-Roy Jenkinson, 2 HJ Luus, 1 Mox Mxoli. Replacements (from): 16 Alandre van Rooyen, 17 Bandisa Ndlovu, 18 Madot Mabokela, 19 Adre Smith, 20 Zandre Jordaan, 21 Gideon van der Merwe, 22 Ashlon Davids, 23 Berton Klaasen, 24 Mzwanele Zito, 25 Johan Momsen, 26 Bjorn Basson.